OnkoSight Advanced^TM for Plasma Cell Myeloma

Plasma cell myeloma is a clonal late B-cell disorder in which malignant plasma cells expand and accumulate in the bone marrow (BM) resulting in cytopenias, bone resorption (lytic bone lesions), and production of serum monoclonal protein.

The diagnosis and sub-classification of the various plasma cell neoplasms depend on the correlation of radiologic imaging data (bone lesions) and laboratory data (M-protein type and amount) with morphologic, cytogenetic, phenotypic, and molecular findings.

OnkoSight Advanced^TM offers simultaneous detection of somatic gene mutations and genome-wide copy number alterations (CNAs), ranging from single-gene changes to entire chromosome aberrations. OnkoSight Advanced^TM NGS helps provide a more detailed evaluation of multiple myeloma genetics for further risk categorization. Furthermore, may help identify additional abnormalities that may be of prognostic and/or therapeutic value.

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